SYNTHESIS, MOLECULAR DOCKING, ADMET STUDY AND IN VITRO PHARMACOLOGICAL RESEARCH OF 7-(2-CHLOROPHENYL)-4-(4-METHYLTHIAZOL-5-YL)-4,6,7,8-TETRAHYDROQUINOLINE-2,5(1H,3H)-DIONE AS A PROMISING NON-OPIOID ANALGESIC DRUG

Introduction: The discovery of novel drugs that can block the transmission of pain signals for treating 2 Piece Power Reclining Sectional the pain of various etiologies is an urgent topic in pharmaceutics.The aim of this paper is to synthesize and to investigate in vitro and in silico characteristics of a promising novel compound: 7-(2-chlorophenyl

Heart murmurs are abnormal heartbeat patterns that could be indicative of a serious heart condition, which can only be detected by trained specialists with the use of a stethoscope.However, it is occasionally the case Neff N90 T68TF6RN0 80cm Induction hob with Wi-fi and TFT Screen that those specialists are not available, resulting in the need for

Congenital heart disease (CHD) is a frequent occurrence, with a prevalence rate of almost 1% in the general population.However, the pathophysiology of the anomalous heart development is still unclear in most patients screened.A definitive genetic origin, be it single-point mutation or larger chromosomal disruptions, only explains about 35% of ident

Abstract Background A comprehensive and agreed-upon definition of vaccine literacy (VL) could support the understanding of vaccination and help policy-makers and individuals make informed decisions about vaccines.Methods To shed some light on this debate and provide clarity, a scoping review was conducted to collect, summarize, and analyse availabl

River baptism has biblical and historical significance in the Christian tradition.Many established mainline churches have baptismal pools where they safely conduct baptism.However, some African-Initiated Churches have been practicing river baptism because of their beliefs, theology and at times a lack of resources.While African-Initiated Churches h